The global Bone Cement & Glue Market in terms of revenue was estimated to be worth $1,644 million in 2023 and is poised to reach $2,248 million by 2028, growing at a CAGR of 6.5% from 2023 to 2028. The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. The growth of this market is majorly driven by the Rising Demand for Minimally Invasive Surgeries with robotic assistance and Growing healthcare sector and Increasing Incidence of Orthopedic Conditions. However, Challenges associated with Variability of pathogen resistance may threat the growth of this market.
Some of the major players operating in this market are Stryker (US), Zimmer Biomet (US) , Smith+Nephew.(UK), DePuy Synthes (a subsidiary of Johnson & Johnson - US) , Enovis (US) , Artivion, Inc (US), Cardinal Health. (US), Medtronic (Ireland), Globus Medical (US), and Heraeus Holding (Germany).
In 2022, Stryker (US), held the leading position in the market. The company’s large share can be attributed to its broad range of Bone cement and strong global presence. Zimmer Biomet (US), held the second position in the Bone cement & glue market in 2022.
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CHALLENGE: Product-related complications.
While bone cement and glue products are generally safe and effective, like any medical intervention, they can be associated with certain complications. Here are some potential complications associated with bone cement and glue:
Infection: Infection is a possible complication following the use of bone cement and glue. Although efforts are made to maintain a sterile surgical environment, there is still a risk of bacterial contamination during the procedure or post-operatively. Infection can lead to implant loosening, prolonged healing, and the need for additional treatments or surgeries.
Allergic reactions: Some individuals may experience allergic reactions to components of bone cement or glue, such as methacrylate monomers. Allergic reactions can manifest as localized inflammation, skin rashes, or more severe systemic reactions. Careful evaluation of patient history and selection of appropriate materials can help mitigate the risk of allergic reactions.
Cement leakage: During the application of bone cement, there is a possibility of cement leakage into surrounding tissues or blood vessels. Cement leakage can lead to complications such as nerve impingement, embolism (if cement enters the bloodstream), or tissue damage. Proper surgical technique and monitoring can help reduce the risk of cement leakage.
Implant loosening: Although bone cement is used to secure implants, there is still a possibility of implant loosening over time. Factors contributing to implant loosening include improper technique, poor bone quality, excessive weight-bearing, or inadequate cement fixation. Implant loosening may require revision surgery to address the instability and ensure long-term implant function.
Adverse tissue reactions: Some individuals may experience adverse tissue reactions to bone cement or glue. These reactions can manifest as chronic inflammation, granuloma formation, or hypersensitivity reactions. The incidence of such reactions is relatively rare, but they can result in discomfort, implant failure, or the need for further interventions.
Thermal necrosis: During the polymerization process of bone cement, heat is generated, which can potentially cause thermal necrosis (tissue damage due to excessive heat) in surrounding tissues. This risk is mitigated by proper cement handling, cooling techniques, and careful monitoring during the procedure.
Likewise, some of the Potential disadvantages of antibiotic-loaded bone cement are as below,
Alteration in the mechanical and structural properties of the bone cement
- Antibiotic resistance
- Allergic reactions
- Systemic toxicity
- Cost implications
Based on Type, the Bone Glue market is segmented into Natural bone glue and Synthetic bone glue. The Natural bone glue segment is anticipated to have the highest shares during. The major factors contributing to the growth of this market are the potential advantages of natural bone glue include better biocompatibility, reduced risk of adverse reactions, and the ability to support tissue regeneration and healing. However, the development and commercialization of natural bone glue products have faced challenges such as standardization, and regulatory approvals.
Based on Loading, the Bone Cement & Glue market is segmented into Antibiotic-loaded bone cement, and non-Antibiotic-loaded bone cement. The Antibiotic-loaded bone cement segment is is anticipated to have the highest shares considering the applications as Antibiotic-loaded bone cement is also commonly used in revision surgeries, where there is a higher risk of infection due to the presence of existing implants, in addition, the effectiveness of antibiotic-loaded bone cement in reducing infection rates has been supported by clinical evidence and guidelines, making it a widely accepted and evidence-based practice. Likewise, Antibiotic-loaded bone cement maintains biocompatibility and bonding strength comparable to plain bone cement, making it a safe and effective option for surgical use.
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The Germany in European Bone cement & glue industry to witness the second highest growth rate during the forecast period.
The Europe bone cement & glue market is segmented into Germany, France, the UK, and the Rest of Europe. Germany is registered the highest growth rate during the forecast period. The major factors contributing to the growth of this market are the high prevalence ofold age population, rising in sport related injuries, orthopedic cases, increasing R&D activities, strategic developments by key players.
